INJECTABLE SEMAGLUTIDE

How supplied: Supplied in (4) prefilled syringes, based off of prescribed dose. Alcohol swabs supplied. USP allows a 45 day Beyond Use Date.

Compound: Semaglutide Injection

Dosing: Recommended dosing follows. Patient specific titations expected. Dosages will depend on each individual.

• Start with 0.25mg for the first 4 weeks and titrate dosing after counsel with your prescriber.

• Medication administered once weekly, on the same day each week. Injections can be done at any time of the day, with or without meals.

• Avoid double dosing to prevent unwanted side effects.

• If a dose is missed, you can take the missed dose up to 5 days after you were originally supposed to take it. If more than 5 days have passed, skip the missed dose and return to original dosing schedule.

Subcutaneous Injection:

• Wash hands and prepare injection site. Clean the injection site with the alcohol swab and let the skin dry.

• Pinch the injection site to create a firm surface.

• Alternate injection sites between either side of the stomach, back of the arm or thigh. Inject two inches from the belly button on either side.

• Insert the needle into the skin between the index finger and thumb at 90 degrees.

• Using a slow and constant pressure, push the plunger rod until it reaches the bottom.

• Gently pull the syringe out of the skin

• Discard of the needle in a sharps container.

Storage:

• Keep Semaglutide injections out of reach of children.

• Once your receive it, store in the refrigerator in-between doses.

• Common side effects:

• Nausea — particularly at initiation and at increase in dose. The nausea can be quite severe.

Recommend the ondansetron ODT that is often co-prescribed. Counsel on proper ondansetron dosing (30 min prior to dose increase and every 4-6 hours after as needed)

• Constipation - very common on this drug increase fiber and water intake. Also consider an OTC stool softener or Miralax if constipation persists.